Since 1996, COYA software (COYA sistemas®) began modeling and developing the first version of the system for clinical analysis laboratories: COYALab, implemented for the first time in December 1999 at Hospital Iturraspe in the city of Santa Fe. Continuous development and technological evolution allowed that what was then only a project was considered today one of the best LIS of the domestic market, encompassing all type of patients, including public and private institutions, with different versions for small, medium and large labs.